
HPE ProLiant Compute Gen12 servers are designed to handle a variety of high-demand workloads, such as artificial intelligence (AI), data analytics, hybrid cloud environments, and virtual desktop infrastructure (VDI) solutions
Hewlett Packard Enterprise (HPE) has launched eight new high-performance servers as part of the HPE ProLiant Gen12 series, enhancing the company’s latest enterprise server portfolio. These new models feature cutting-edge technologies designed to optimize enterprise performance, boost security, and streamline management using artificial intelligence (AI). The servers, which will be equipped with the upcoming Intel Xeon processors, are set to meet the demanding requirements of data centers and edge environments across industries such as finance, healthcare, and more.
Next-gen security and performance features
The ProLiant Gen12 servers mark a major step forward in enterprise IT security, introducing industry-first capabilities aimed at mitigating the growing threat landscape. At the heart of the Gen12 portfolio is the enhanced HPE Integrated Lights Out (iLO) 7, featuring a secure enclave designed from the ground up as HPE intellectual property. This secure enclave provides quantum computing-resistant protection, ensuring that the servers are equipped to handle future security challenges.
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HPE’s commitment to security is further demonstrated by its holistic approach to safeguarding data, incorporating security measures throughout the product lifecycle, from the chip to the cloud. The secure enclave, embedded directly into the server hardware, creates an unbreakable chain of trust to guard against firmware attacks, while offering full visibility across HPE’s trusted supply chain.
In addition to security enhancements, the Gen12 servers deliver up to 65% better power savings annually compared to legacy systems. Designed to address the increasing power demands of modern workloads, these high-performance servers deliver up to 41% improved performance per watt, supporting energy-efficient operations without compromising on performance. With Intel Xeon processors powering the systems, these servers are engineered to handle even the most resource-intensive tasks across various industries.
AI-powered management and energy optimization
HPE ProLiant Compute Gen12 servers are optimized for a wide range of demanding workloads, including artificial intelligence (AI), data analytics, hybrid cloud environments, and virtual desktop infrastructure (VDI) solutions. To ensure seamless management and energy efficiency, HPE has introduced its cloud-based Compute Ops Management platform, which uses AI to provide predictive automation and insights into server health, energy usage, and carbon emissions.
These new management features aim to enhance operational efficiency by forecasting energy consumption, offering businesses the ability to set cost and emissions thresholds. Additionally, the new AI-driven insights will help organizations identify potential server issues across distributed IT environments, reducing downtime by up to 4.8 hours per server annually. Through server lifecycle management, HPE is helping enterprises effectively manage their IT infrastructure from deployment to decommissioning, ensuring that servers perform optimally for the duration of their use.
To support customers' sustainability goals, HPE has also introduced optional direct liquid cooling (DLC) for the Intel-based HPE ProLiant Compute Gen12 servers. Direct liquid cooling offers significant advantages over traditional air cooling by efficiently removing heat and enabling better energy efficiency, a critical factor as data centers continue to scale.
Sustainable and scalable solutions
Hewlett Packard Enterprise’s continued focus on sustainable solutions is reflected in its efforts to address customer demand for more energy-efficient data centers. By implementing DLC, HPE aims to help organizations reduce energy costs while maintaining optimal enterprise performance.
The ProLiant Gen12 servers will be available in several configurations, including the HPE ProLiant Compute DL320, DL340, DL360, DL380, and ML350 Gen12 models, which will be released in Q1 2025. The HPE Synergy 480 and HPE ProLiant Compute DL580 Gen12 models are expected to arrive in Summer 2025.
Customers can choose from standalone servers or HPE GreenLake, a scalable as-a-service platform that provides greater agility and cost efficiency. These solutions are available through authorized channel partners, and HPE Services will assist clients with advisory, professional, operational, and financial services to help optimize the new Gen12 servers for maximum business impact.
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